Masahiro Kobayashi Selected Research

adefovir dipivoxil (Hepsera)

6/2014	Long-term efficacy and emergence of multidrug resistance in patients with lamivudine-refractory chronic hepatitis B treated by combination therapy with adefovir plus lamivudine.
3/2014	Renal dysfunction and hypophosphatemia during long-term lamivudine plus adefovir dipivoxil therapy in patients with chronic hepatitis B.
2/2010	Development of HCC in patients receiving adefovir dipivoxil for lamivudine-resistant hepatitis B virus mutants.
1/2008	Virological response and hepatocarcinogenesis in lamivudine-resistant hepatitis B virus genotype C patients treated with lamivudine plus adefovir dipivoxil.
5/2007	Factors associated with the virological response of lamivudine-resistant hepatitis B virus during combination therapy with adefovir dipivoxil plus lamivudine.
1/2004	Adefovir dipivoxil for treatment of breakthrough hepatitis caused by lamivudine-resistant mutants of hepatitis B virus.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Masahiro Kobayashi Research Topics

Disease

95	Hepatocellular Carcinoma (Hepatoma) 09/2023 - 01/2002
54	Infections 01/2021 - 01/2002
49	Chronic Hepatitis C 12/2020 - 01/2002
48	Chronic Hepatitis B 02/2022 - 01/2002
45	Fibrosis (Cirrhosis) 09/2023 - 01/2002
34	Neoplasms (Cancer) 04/2022 - 01/2002
29	Liver Cirrhosis (Hepatic Cirrhosis) 01/2021 - 01/2002
26	Hepatitis 01/2014 - 01/2002
20	Liver Diseases (Liver Disease) 10/2022 - 01/2002
17	Chronic Hepatitis (Chronic Active Hepatitis) 03/2014 - 01/2003
15	Hepatitis B 01/2022 - 01/2002
15	Non-alcoholic Fatty Liver Disease 01/2022 - 01/2011
11	Type 2 Diabetes Mellitus (MODY) 04/2024 - 03/2009
11	Carcinogenesis 01/2014 - 01/2003
10	Hepatitis C 03/2016 - 09/2005
9	Anemia 01/2023 - 07/2004
8	Liver Neoplasms (Liver Cancer) 04/2022 - 12/2010
8	Diabetes Mellitus 01/2022 - 11/2008
7	Body Weight (Weight, Body) 09/2023 - 10/2007
5	Lymphoma (Lymphomas) 12/2019 - 04/2003
5	Viremia 01/2017 - 01/2007
4	Thrombocytopenia (Thrombopenia) 01/2023 - 05/2009
4	Inflammation (Inflammations) 04/2022 - 01/2003
4	Virus Diseases (Viral Diseases) 04/2021 - 01/2004
4	Neoplasm Metastasis (Metastasis) 10/2018 - 04/2002
4	Hypertension (High Blood Pressure) 03/2014 - 09/2009
4	Disease Progression 01/2014 - 01/2004
3	Fatty Liver 04/2022 - 09/2009
3	Insulin Resistance 01/2022 - 06/2009
3	Wounds and Injuries (Trauma) 01/2021 - 07/2004
3	Hepatic Encephalopathy 12/2019 - 10/2004
3	Persistent Infection 10/2013 - 05/2005
3	Liver Failure 09/2012 - 01/2004
2	Cholangitis 03/2024 - 02/2024
2	Chemical and Drug Induced Liver Injury 11/2023 - 10/2022

Drug/Important Bio-Agent (IBA)

66	InterferonsIBA 12/2020 - 01/2002
34	Lamivudine (Epivir)FDA Link 05/2017 - 01/2002
32	Ribavirin (Virazole)FDA LinkGeneric 01/2018 - 01/2002
27	Antiviral Agents (Antivirals)IBA 01/2021 - 01/2004
27	RNA (Ribonucleic Acid)IBA 01/2019 - 01/2003
24	DNA (Deoxyribonucleic Acid)IBA 04/2022 - 02/2002
23	Hepatitis B e AntigensIBA 03/2014 - 01/2002
16	lenvatinibIBA 04/2022 - 11/2018
16	Hepatitis B Surface Antigens (HBsAg)FDA Link 01/2022 - 01/2002
15	Alanine Transaminase (SGPT)IBA 03/2016 - 01/2003
11	entecavir FDA Link 01/2022 - 06/2007
10	AntigensIBA 01/2022 - 01/2002
9	alpha-Fetoproteins (alpha-Fetoprotein)IBA 02/2020 - 01/2003
9	Amino Acids FDA Link 09/2015 - 08/2008
8	BilirubinIBA 10/2017 - 01/2003
7	miriplatinIBA 06/2017 - 01/2011
7	Transaminases (Aminotransferases)IBA 03/2012 - 08/2004
6	Biomarkers (Surrogate Marker)IBA 04/2022 - 12/2007
6	Aspartate Aminotransferases (Aspartate Transaminase)IBA 01/2022 - 08/2008
6	AlbuminsIBA 01/2019 - 01/2009
6	Serum AlbuminIBA 10/2017 - 10/2007
6	telaprevirIBA 10/2014 - 01/2010
6	adefovir dipivoxil (Hepsera)FDA Link 06/2014 - 01/2004
6	Interferon-alpha (Interferon Alfa)IBA 05/2014 - 02/2002
6	Interferon-betaIBA 01/2011 - 01/2008
5	Fetal Proteins (Fetoprotein)IBA 04/2021 - 09/2013
5	lipoarabinomannan (LAM)IBA 05/2017 - 06/2008
5	daclatasvirIBA 01/2017 - 05/2014
5	asunaprevirIBA 01/2017 - 05/2014
5	adefovirIBA 06/2014 - 01/2004
5	gamma-Glutamyltransferase (gamma-Glutamyl Transpeptidase)IBA 01/2011 - 01/2006
4	NucleotidesIBA 02/2022 - 09/2004
4	Sodium-Glucose Transport ProteinsIBA 01/2022 - 01/2017
4	Sorafenib (BAY 43-9006)FDA Link 02/2021 - 06/2019
4	CreatinineIBA 08/2017 - 03/2013
4	Protease Inhibitors (Protease Inhibitor)IBA 01/2017 - 01/2010
4	Dihydrotachysterol (AT 10)IBA 01/2014 - 03/2009
4	Aspartic Acid (Aspartate)FDA Link 04/2010 - 05/2004
4	Proteins (Proteins, Gene)FDA Link 01/2010 - 03/2006
3	Prednisolone (Predate)FDA LinkGeneric 01/2024 - 10/2022
3	SodiumIBA 09/2023 - 11/2015
3	Hemoglobins (Hemoglobin)IBA 01/2023 - 11/2004
3	Adrenal Cortex Hormones (Corticosteroids)IBA 10/2022 - 02/2002
3	Cell-Free Nucleic AcidsIBA 04/2022 - 12/2020
3	Surface Antigens (Surface Antigen)IBA 01/2022 - 12/2002
3	CanagliflozinIBA 01/2022 - 05/2019
3	TransferasesIBA 04/2021 - 08/2004
3	Tenofovir (Viread)FDA Link 04/2021 - 01/2014
3	Glucose (Dextrose)FDA LinkGeneric 02/2020 - 06/2012
3	SofosbuvirIBA 01/2018 - 01/2017
3	NucleosidesIBA 05/2017 - 06/2007
3	PlatinumIBA 03/2013 - 04/2009
3	Tyrosine (L-Tyrosine)FDA Link 04/2010 - 05/2004
3	Methionine (L-Methionine)FDA Link 04/2010 - 05/2004
2	SuspensionsIBA 01/2024 - 03/2012
2	Tolvaptan FDA Link 09/2023 - 11/2015
2	Vasopressin Receptors (Arginine Vasopressin Receptor)IBA 09/2023 - 11/2015

Therapy/Procedure

140	Therapeutics 03/2024 - 01/2002
17	Radiofrequency Ablation 02/2019 - 01/2002
8	Drug Therapy (Chemotherapy) 01/2021 - 02/2006
6	Aftercare (After-Treatment) 01/2022 - 12/2006
5	Retreatment 03/2019 - 04/2003
5	Drug Tapering 10/2013 - 07/2004
4	Hepatectomy 09/2023 - 11/2017
3	Electrodes (Electrode) 02/2019 - 01/2016